

Your doctor will check your blood counts regularly during treatment with TASIGNA. Low Blood Counts: Low blood counts are common with TASIGNA but can also be severe.You should follow your doctor’s instructions. Your doctor may have you stop TASIGNA for some time or lower your dose if you have side effects. These tests will check your heart, blood cells (white blood cells, red blood cells, and platelets), electrolytes (potassium, magnesium), cholesterol, blood sugar, and pancreas and liver function. During treatment with TASIGNA your doctor will do tests to check for side effects.

TASIGNA can cause serious side effects that can even lead to death. Avoid grapefruit, grapefruit juice, and any supplement containing grapefruit extract while taking TASIGNA.Avoid eating food for at least 2 hours before the dose is taken, and avoid eating food for at least 1 hour after the dose is taken.This may increase your chances for serious and life-threatening side effects. Food and grapefruit products increase the amount of TASIGNA in your body.Do not take any other medicine while taking TASIGNA unless your doctor tells you it is okay to do so TASIGNA can interact with many medicines and supplements.Do not take TASIGNA if you have long QTc syndrome or low levels of potassium or magnesium in your blood.Your doctor should check your heart with a test called an electrocardiogram (ECG).These can be symptoms of QTc prolongation. Call your doctor right away if you feel lightheaded, faint, or have an irregular heartbeat while taking TASIGNA. QTc prolongation causes an irregular heartbeat, which may lead to sudden death. QTc Prolongation and Sudden Death: TASIGNA can cause QTc prolongation, a possibly life-threatening heart problem.
